产品货号：
Z10599
中文名称：
AKIRIN1抗体
英文名称：
Anti-AKIRIN1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AKIRIN1 Antibody |
| 指标别名 | STRF2,C1orf108,Akirin-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | AKIRIN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Akirin1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human Akirin1.The immunogen is located within the first 50 amino acids of Akirin1. |
| 计算分子量 | 22kDa |
| 成分 | Akirin1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Akirin1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The highly conserved,nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-百B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-百B pathways.Akirin1 is dispensable in the mouse,and neither knockout mice nor cells derived from them have obvious distinctive phenotypes.In contrast,Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR),TNF-汐and IL-1汕signaling,and for the production of IL-6.Akirin2 is functionally closer to the single gene in Drosophila,as the homozygous null D.melanogaster Akirin mutants show a similar,mid-to-early embryonic death. |
| Uniprot ID | Q9H9L7 |
| 基因名全称 | Akirin 1 |
| 蛋白名全称 | Akirin 1 |
| 推荐稀释比 | Akirin1 antibody can be used for detection of Akirin1 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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